The Proof is in the Product

Texas feedlot manager describes her positive experience with
ZACTRAN® (gamithromycin)

With today’s tight cattle inventory, it’s critical that every investment provides the best possible return. Animal health manager Diana McElroy with Nortex Feedlot has been in the cattle business for 20 years, and she knows the impact products can have on the bottom line. Recently, she saw firsthand her return on investment by incorporating ZACTRAN® (gamithromycin) into her operation in Dalhart, Texas.

Prescription ZACTRAN, Merial’s rapid response weapon in the battle against Bovine Respiratory Disease (BRD) in high-risk cattle, is labeled as a first-pull treatment for all major pathogens of BRD in beef and non-lactating dairy cattle. It is also labeled to control BRD associated with Mannheimia haemolytica and Pasteurella multocida in beef and non-lactating dairy cattle.1 McElroy says they started using ZACTRAN after conducting a trial against their then current arrival antibiotic protocol. After reviewing the data from the trial, their consulting veterinarian recommended ZACTRAN as the new antibiotic protocol.

“We are a 30,000-head operation, and start a lot of high-risk cattle here year around. We first started using ZACTRAN on arrival,” McElroy says. “After working with the product and seeing the positive results, we have now decided to use it as our first-treatment antibiotic.”

“To increase a producer’s bottom line, cattle need to respond quickly to treatment, and they can be confident in ZACTRAN,” 2,3 says Bruce Nosky, DVM, director of large animal veterinary services, Merial. “In field studies conducted for initial product approval, cattle treated with ZACTRAN showed a rapid improvement in BRD clinical signs and more than three-quarters of the cattle with a fever had a significant decrease in temperature within 24 hours.”4

When McElroy began using ZACTRAN in her treatment protocol, she could see a noticeable difference. “The cattle looked a lot healthier very quickly, and we were able to move them out of the hospital pen sooner.”

Additional advantages McElroy noted were convenience and the packaging. “The product is very easy to use because you only give one injection compared to multiple,” McElroy says. “Also, each bottle of ZACTRAN I receive comes with a durable bottle cover, which provides me peace of mind that the antibiotic is protected.”

McElroy also mentioned the product has a long duration in their cattle, with the result being fewer treatments. In field trials for BRD treatment, the majority of high-risk cattle that received ZACTRAN remained healthy as assessed on day ten of the study. 3 In additional studies for BRD control, the majority of lightweight, long-haul and high-risk cattle that received ZACTRAN on arrival showed significantly less disease during the 10-day study compared to non-treated cattle. 5

“In today’s cattle industry, it is imperative to employ sound health protocols, and ZACTRAN has definitely helped increase our bottom line,” McElroy says. “We are saving money by raising healthier cattle. The proof is in the product.”

Producers can learn more about ZACTRAN by contacting their veterinarian or visiting

IMPORTANT SAFETY INFORMATION: For use in cattle only. Do not treat cattle within 35 days of slaughter. Because a discard time in milk has not been established, do not use in female dairy cattle 20 months of age or older, or in calves to be processed for veal. The effects of ZACTRAN on bovine reproductive performance, pregnancy and lactation have not been determined.

About Merial

Merial is a world-leading, innovation-driven animal health company, providing a comprehensive range of products to enhance the health, well-being and performance of a wide range of animals. Merial employs approximately 5,600 people and operates in more than 150 countries worldwide. Its 2011 sales were more than $2.8 billion. Merial is a Sanofi company. For more information, please see

®ZACTRAN is a registered trademark of Merial Limited. ©2012 Merial Limited, Duluth, GA. All rights reserved. RUMIOTD1241 (07/12).

1 ZACTRAN product label.

2 Lechtenberg K, Tessman R, Chester S. Efficacy of gamithromycin injectable solution for the treatment of Mycoplasma bovis induced pneumonia in cattle. Intern J Appl Res Vet Med. 2011;9(3):233-240.

3 Sifferman RL, Wolff WA, Holste JE, et al. Field efficacy evaluation of gamithromycin for treatment of bovine respiratory disease in cattle at feedlots. Intern J Appl Res Vet Med. 2011;9(2):171-180.

4 Data on file at Merial.

5 Lechtenberg K, Daniels CS, Royer GC, et al. Field efficacy study of gamithromycin for the control of bovine respiratory disease in cattle at high risk of developing the disease. Intern J Appl Res Vet Med. 2011;9(2):189-197.

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