What is BRD?

Bovine respiratory disease is a serious illness in cattle

Bovine respiratory disease (BRD) occurs when environmental and other stressors weaken a calf’s immune system to cause what is essentially pneumonia in calves.

Because transportation is particularly stressful for cattle, BRD is often known as shipping fever. Other stressors can include weaning and commingling, as well as dust, temperature, moisture and inadequate ventilation.

Signs of bovine respiratory disease

BRD-causing bacteria, such as Mycoplasma bovis (M. bovis) or Pasteurella multocida (P. multocida) in cattle, can be present even in the healthiest calf or cow respiratory system. Stressful situations can compromise the immune response allowing bacteria reach the lungs. When this happens, common signs to look for include mucus, runny nose and fever. When left untreated, BRD can be fatal.

A smart solution

The smart way to treat BRD is with ZACTRAN® (gamithromycin). With one easy injection, ZACTRAN provides a response within 24 hours, and BRD treatment and control for up to 10 days.1,2


Merial is now a part of Boehringer Ingelheim. ®ZACTRAN is a registered trademark of Merial. ©2017 Merial, Inc., Duluth, GA. All rights reserved. RUMIOTD1714 (1/17)

1Sifferman RL, Wolff WA, Holste JE, et al. Field efficacy evaluation of gamithromycin for treatment of bovine respiratory disease in cattle at feedlots. Intern J Appl Res Vet Med. 2011;9(2):171-180.

2ZACTRAN product label.

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